Skull Base Centre

Diseases and disorders of the sinonasal areas, ears and skull base, such as benign and malignant tumours (cancers), infections, congenital defects and complicated head trauma, are rare and potentially life-threatening. These conditions can affect sensory and neurological faculties of vital importance, such as the sense of smell, vision, hearing, balance and cerebral functions. The complex anatomy of the cranial base means that treatment is a challenge, and must be offered with utmost care and expertise.

Why choose for treatment at the Skull Base Centre at Erasmus Medical Centre in the Netherlands?

The Erasmus MC is the largest tertiary care and academic hospital in the Netherlands, and its skull base team has been a leader in the field since its inception in 2009. Our hospital can proudly offer the services of highly specialized medical professionals for the treatment of complex and rare diseases.

What we do at the Skull Base Centre at Erasmus MC

We at the Skull Base Centre are committed to provide the best possible treatment of disorders at the skull base with the highly skilled and experienced physicians at the Erasmus MC hospital. After proper diagnosis, our patients are discussed during multidisciplinary skull base (tumour) board meetings. Our team works to find the technique or combination of techniques with the highest chance of being cured and ability to return to normal life.

Our centre is the only one in the Netherlands to combine the Ear, Neck and Throat medicine (ENT), Neurosurgery, Radiology and Radiotherapy departments.

We treat :

  • Adenoma (pituitary tumours)
  • Angiofibroma
  • Chordoma
  • Craniopharyngioma
  • Meningioma
  • Olfactory neuroblastoma
  • Nasopharyngeal carcinomas
  • Carcinomas of the nasal cavity and sinonasal regions
  • Carcinomas of the ear and middle skull base
  • Sinonasal melanomas
  • Neurofibromas
  • Schwannomas
  • Parangangliomas
  • CSF leakages (cerebrospinal fluid leak)

Please feel free to contact us for any complex skull base disease or disorder!


Depending on the type of tumour or disease and the specific location, there are many different treatment approaches ( surgical and non-surgical) that can be implemented.


Surgical treatment includes both open (external skin incisions) and minimally invasive (without incisions) techniques. Our surgeons at the Skull Base Centre have vast experience in both open techniques and minimally invasive approaches to the skull base and brain. Our surgeons have been specially trained to use high-definition telescopes, intraoperative neuro-navigation and specialized instruments to safely perform surgery at the skull base and surrounding regions.

Radiation Therapy

Our radiation and medical oncologists have the expertise and experience on the latest radiotherapy techniques and alternative treatment options for a wide variety of lesions. The Erasmus Medical Centre/Holland Proton Therapy Centre will be the first treatment centre in the Netherlands to offer proton therapy as a cancer treatment. We are proud to offer patients from all over the world access to this new cancer treatment option.

For extensive information on radiation therapy options at the Erasmus MC, please visit our Radiation Oncology page

Skull Base Centre Follow-up Care

All skull base patients are scheduled for several follow-up appointments that include a post-operative check-up and surveillance. In addition, we provide various support services, such as rehabilitation and speech therapy. In collaboration with (inter)national patient organisations, we ensure that each patient receives proper follow up and a support system.

More about the Skull Base Centre at Erasmus MC

Our Team

To ensure that our patients at the Skull Base Centre receive the most comprehensive care, we have established a multidisciplinary team of neurosurgeons, head and neck surgeons, neurologists, microvascular reconstructive surgeons, interventional radiologists, radiation oncologists, pathologists, and medical oncologists, who work together to offer an optimal personalized treatment path for each patient.

Our Medical Expertise

We at the Skull Base Centre validate our own treatment protocols through clinical outcome research, and we update them regularly according to new evidence and institutional experiences. The skull base team trains the next generation of physicians, nurses and other health care providers from within the region and the rest of the world through continuous educational seminars, international courses and fellowships.

The skull base centre is recognised by the NFU ( the Dutch Federation for University Medical Centres) as one of the centres for rare diseases in the Netherlands and is an active member of EURACAN (European Reference Network for Rare Cancers).

Throughout the years we have established intensive collaboration with other healthcare establishments and patient organisations within Europe, for both patient care and research purposes. Our goal is to improve your quality of life by providing the highest quality treatment in a caring environment.

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